The datacenter stuff is on a different architecture and driver stack. The number one supercomputer on the top500 list (frontier at ORNL) is based on AMD GPUs and AMD is probably more invested in supporting that.
Frontier certainly has some unique quirks but the documentation is online[0] and most of these quirks are inherent to the kinds of fundamental issues you'll see on any system in the space (SLURM, etc).
However, most of the issues are fundamentally ROCm and you'll run into them on any MIxxx anywhere. I run into them frequently with supported and unsupported consumer gear all the way up.
[0] - https://docs.olcf.ornl.gov/systems/frontier_user_guide.html
I got an appointment and have exactly one minute till I have to leave, apologies for brevity: they can't open source the full driver because then they'd have to release HDMI spec stuff that the consortium says they can't. (I don't support any of that, my only intent is to communicate George isn't really locked in here when he starts casting aspersions or claiming AMD doesn't care)