It makes me a little sad, because we're in this frustrating position of knowing how "effectively unlimited" the universe is, but also knowing how impossible it is to realistically explore it, at least not without a fundamental change to our understanding of physics.
I think it'd be cool to set up colonies on other planets, or hell, other solar systems, but the inability to communicate seems like a pretty hard blocker. I mean, even sticking to the solar system, will start taking six hours for the light to even reach earth from Pluto, assuming it can even have a direct path.
I don't know anything about physics, so I was hoping that the entanglement hypothesis might allow us to fix that, but clearly that wasn't the case. This makes me sad.