In that case, it sounds like most startup founders are immoral by your definition. The vast majority of startups make decisions based on ideas they have about people which are not proven, i.e. "people would like to rent out their home to strangers".

...but if you do it by thinking that those things are natural to the gender, the become immoral.

What if you don't know whether those things are natural to the gender or learned, but make decisions based solely on predicted (or demonstrated) consumer behavior? I.e., "these pink cars sell really well, mostly to girls, I have no idea why. Lets make more and market them widely."

Or what if you are just testing hypothesis? "Lets try out pink cars, aliens, babies, pirates and zombies, and then see what sells." Would that be immoral? It certainly lacks the certainty you seem to want, but it is how many businesses make decisions.