To know whether a heat pump (air-to-water) can replace that boiler effectively and maintain comfort, I had to find out whether the house would be comfortable with water temps of 135°F or so. Is there an amount of “that’s just looking at the building construction” to make that analysis? I think maybe technically yes, but practically no.
As it was, to get an answer, I abused my old boiler by turning the water temps down (causing condensation and slow damage [planning to replace it anyway]) and seeing what happened on cold days.