That’s not to include the possibility that there’s certain manufactured goods that could be cheaper or only possible to produce at lower gravity.
Landing on the moon is a very different endeavour than simply reaching Earth orbit from Earth. In order to refuel and reuse rockets on the moon, you'd need to build out all the infrastructure for doing so first, not to mention the resources necessary for continuous operation. Even getting running water on the moon would be a huge logistical and infrastructure challenge, let alone operating a launch pad.
Anyone that wants to intuitively understand these challenges can simply play Factorio's Space Exploration mod (https://mods.factorio.com/mod/space-exploration).
> Energetically, it costs less to shoot your payload out of the Solar System (from a positive gravity assist with planets like Jupiter) than it does to shoot your payload into the Sun.
This is kind of my point regarding the Moon. It's harder to hit the Moon than to miss it, so why aim for it?
[1]https://projectrho.com/public_html/rocket/surfaceorbit.php