The reverse-engineering issue was popularized by this article,
https://www.cell.com/cancer-cell/fulltext/S1535-6108%2802%29...
On the second point, the failure of Openworm to model the very well-mapped-out C. elegans (~0.3k neurons) says a lot.
On the second point, the failure of Openworm to model the very well-mapped-out C. elegans (~0.3k neurons) says a lot.