I may be alone in this, but I think these threats like jailtime for fraudulent research would have the side effect of discouraging researchers that don't even engage in that stuff. I think pulling out the pitchforks is a misguided idea, and it's a shame that it's so common today.
On one hand, these people have a big responsibility to do good work and stay out of trouble for the sake of the ones they're helping (i.e. Alzheimer's patients), but on the other hand their impact depends a lot on their mental/emotional state -- if you put more bs in their mental buffer, it's naturally going to mess with them and lead to a decline in quality. They have to focus.