Node.js 0.8 sounds great, though I'm afraid there will again be a long period where many of your NPM dependencies are simply broken, especially with the new build tool for native modules:
https://github.com/TooTallNate/node-gyp
We had a bit of a similar situation with the transition from 0.4 to 0.6 because of some API changes, especially the removal of EventEmitters from the C++ module API: https://groups.google.com/d/topic/nodejs/rmvA434u3Dk/discuss...
Hopefully this time it will happen more smoothly.