See page 10, Figure 5: Price of paper/CPI in England, 1356-1869, and the Netherlands, 1450-1800.
This shows that the price of paper declined exponentially from 1350 to 1650. The decrease in the cost of paper made printing economical. Printing on vellum was not. They point out that each Gutenberg Bible printed on vellum required the skins of 300 sheep.