I'm bothered by Jeff's attitude that a game made by a bigger company is somehow more deserving of piracy.
Is this an actual effect? I feel like doing an experiment.
This example is a fairly mainstream idea... it made an appearance in the South Park movie.
If A is the set of people that've heard of your product sans piracy, and B is the people that've heard of it after piracy, then the gap between B' that pirates and B had better be smaller than the gap between A and B. That's likelier for a tiny producer than a huge one.
Big guys have free advertising from piracy, small guys are hurt from the same thing.
Edit: I guess we mis-understand each other -- I didn't mean VERY small guys, who may suffer from obscurity.