For any commercial company, those are not corner cases!
I am not sure I totally understand what you mean: yes, the lockfile might be messed up, but is the environment working? I'm a bit blessed because I don't have CUDA on my machine so I save myself a lot of hassle.
I am trying to submit an improvement to the docs about this. https://github.com/astral-sh/uv/pull/6523 I'd love to hear your feedback.
BTW, there is a proposal to standardise the lockfile format in Python: https://discuss.python.org/t/pep-751-lock-files-again/59173/...