Doesn't Micropython already get you 95% of the way towards just running the same Python code on multiple MCUs?
So yeah not everything under the sun, but certainly not what I'd consider a "very small" number of MCUs.
Of course, support level varies among the platforms, but you're not going to be doing too fancy things in MicroPython I imagine.
[1]: https://github.com/micropython/micropython?tab=readme-ov-fil...
[2]: https://docs.zephyrproject.org/latest/boards/index.html