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I don't have a strong opinion on the whole, but as someone who's been building a diagramming app for 2+ years, I've found react-flow to be the most solid free & open-source node-based diagram component, by far. At least in terms of quantity/quality of features and UX/DX. Though admittedly I haven't thoroughly looked at alternatives in about a year.

It basically singlehandedly convinced me that the ecosystem was worth going with react when I started my project, despite really enjoying svelte.

Framer Motion, react-three-fiber, react dnd, just a few that come to mind.

All those libraries also work in React of course. The only vanilla js libraries that don't work well with React are UI libraries that assume they can control the DOM. But I can't think of many of those I'd prefer to the many excellent React UI libraries.