What ever happened to that, by the way? So far the only big companies to come out of Russia were basically local language counterparts of Yahoo, Facebook and Norton.
What's about Parascript (acquired for $50M in 2008)? http://www.crunchbase.com/company/parascript
Abbyy? http://www.crunchbase.com/company/abbyy
Evernote? Badoo? Parallels?
Also, the fact that a 50m company even needs to be mentioned among the "top" should be sufficient proof of the country's impact on the rest of the world (again, I'm not counting Russia-specific Yandex/Rambler/Odnoklassniki/[...] here)