Even if you add noise to your simulation , when you go to the real world it will have lots of sources of noise and errors that you didn't model. In this case I suspect aligning the CT scan with the ultrasound probe will be extremely difficult.
Also there's a reason ultrasonographers are so highly paid, and it's mostly used for pregnancies. In normal tissue it kind of sucks as an imaging method. (On an absolute scale; obviously it's amazing technology.)
Eh maybe it will work though. You never know.