If the US population has doubled since 1980, then it wouldn't be surprising that some population-level statistic (total pedestrian deaths) is at an all-time high! And it could still be at an all-time high while reflecting a substantial increase in safety - if the population doubled (increased 100%) but deaths only rose 25%, for instance.
Similarly, I anecdotally observe that cycling is more popular than it was 20 years ago. So it would not be surprising (to me) to observe that cycling deaths are higher as well.
But without quantifying any of these factors, the significance of these statistics is difficult to evaluate.