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Hackers may be interested in the story of Jaimie Heywood, who when his brother was diagnosed with ALS started his own garage-biotech company to try to find a cure. Sadly the brother died but the effort lives on and Jaimie went on to start PatientsLikeMe.com.

http://en.wikipedia.org/wiki/James_Heywood_(chief_executive) http://westcityfilms.com/smsf.html

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See especially Jamie's TEDx talk. "Wouldn’t it be great if the technology we used to take care of ourselves was as good as the technology we use to make money?"

http://www.ted.com/talks/jamie_heywood_the_big_idea_my_broth...

And to bring it back full circle to HN: Once original Basecamp sunsets, we think PatientsLikeMe has the oldest continuously-running Rails app; the oldest commits are from 2005, running Rails 0.5.

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