edit: The thing is, had I prefaced it with "ASSUMING A PROPERLY FUNCTIONING COMPUTER," someone would still roll in to pick it apart. You can't please pedants and make a worthwhile point at the same time.
Do circuits get weird? Can a stray cosmic ray flip a bit even in a system with ECC RAM?
Sure.
Does this meaningfully affect a bit about the hazards of abstractions on top of abstractions?
No.
The point is that abstractions amplify computer problems whether they're human error or ghosts in the machine.