I agree with this for _purchasing_ things, but not aggregating. I use a lot of these services to aggregate results and then visit airlines/hotels independently to see if the price is reasonable.
Last year, we had around 70 days and this year we are looking at between 60-70 days.
At that point, hotel loyalty has benefits - loyalty points for free hotel stays , seat upgrades for flights and hotel room upgrades, lounge access when you fly a preferred airline etc.
Right now, if at all possible and the rates aren’t too much different, I’m going to stay in Hilton or Hyatt brand hotels. While I don’t care about 5 star hotels, I’m not staying at a Days Inn.
This isn't the case with airline miles; you get them either way, it seems. But there are often other benefits (eg, you get 5x miles if you book with your airline credit card directly through the airline).
OTOH, I prefer to purchase tickets directly with the airline because dealing with them directly when something happens is way better compared to having the OTA in the middle. Sometimes paying a small difference is worth the peace of mind.
And then they lost our luggage (tents and all), but that's another story.