https://en.wikipedia.org/wiki/Nobel_disease
It's hardly limited to Nobel laureates. But it's certainly a strong marker that somebody had indeed tremendous scientific skills, and then failed utterly to apply that ability later.
See also: Engineer's disease.
> https://en.wikipedia.org/wiki/Nobel_disease
I'm kinda not a fan of the list there, since it tries to tar a few early-20th century folks with connections with ESP and parapsychology, but my understanding is those ideas weren't as kooky back then as they are now.
You see this wherein he has mostly avoids ruining spacex because he knows he isn't a rocket scientist but absolutely wrecks Twitter because he thinks he understands it.
See also his delusions about mars, desire to use a minisub in a cave rescue so tight divers had to remove tanks, stopping services needed for 2FA, and suggestion for relay satelites between earth and mars to communucate faster.
He's absolutely intellectually average with a way above average personality, ego, and wallet.
You don't think one of the world's foremost statisticians should have felt that he was qualified to participate in a purely statistical argument?
We reward and give status to scientists that come up with answers and the people doing the hard framing work not so much. The two guys that used standard crystallography techniques to figure out DNA is a double helix got the Nobel prize. The lady that figured out how to crystalize DNA and get the films is completely ignored.
So yeah top scientists high on their own ego will totally biff it when dealing with some other field they know nothing about.
The reason W&C won the prize is that not only did the propose the (close to correct) structure, they realized it was a antiparallel double helix, and deduced the underlying mechanism for genetic replication: "It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material." and also made a few key observations about isomerization in bases that allows for G/C and A/T pairing to be specific.
Crick was a genius, although he also went off-piste with panspermia, and Watson is just an asshole. Franklin was a great scientist but it's not clear at all that she should have or would have received the prize.