I've been working with C# since 2001, which is when it came out of beta stage and into production-ready.
My last greenfield product I was able to choose the stack (except the database, which I was stuck with).
Front-end? Angular, mostly because I felt it fit best with experienced .Net developers.
Back-end API layer? C#, obviosly.
So I've been working with C# for 24 years. No regrets.