I was curious as how "transferable" spatial memorization in a video game in the form of a "virtual memory palace" would be since the conventional approach is based off physically real familiar locations.
Surprisingly I found using a combination of memory palaces built off video game levels in conjunction with a PAO approach towards compressing three numerical values into a single visual image to be highly effective - though I mostly used it for parlor tricks like memorizing a randomly shuffled deck.
If you're interested in learning more about the memory competitions, memory palaces, etc. I highly recommend the book "Moonwalking with Einstein":