I would dispute the relative significance or meaning of those changes though. We can build dams and tall buildings. We can cure diseases and develop elaborate communications infrastructure.
I don't see that these developments alter our essential humanity though. If you read any classic literature from 100, 200, or even 1000 years ago, the emotional truths resonate the same way.
These developments sure altered my humanity. By making it possible.
Also I'm not sure where Rationalists or transhumanists said "it would be cool to live way longer" and you read "get rid of love." That seems like a weird failure of your own imagination. You can't have love if you're dead, so the transhumanists want you to live longer and... experience more love!
That just means that field can be static (or just updated for modern references). It doesn't mean there aren't lots of things to improve in other areas.