A basic thing to remember: Any given dense model would require X GB of memory at 8-bit quantization, where X is the number of params (of course I am simplifying a little by not counting context size). Quantization is just 'precision' of the model, 8-bit generally works really well. Generally speaking, it's not worth even bothering with models that have more param size than your hardware's VRAM. Some people try to get around it by using 4-bit quant, trading some precision for half VRAM size. YMMV depending on use-case