Bullets fall down and can be deadly, so anyone doing so should at least be prosecuted for reckless endangerment if not assault with a deadly weapon.
At least one Florida man is out there plinking Walmart drones at 400 feet with a 9mm. Saw another who took one down from a boat also with a pistol (probably 9mm also), but can't find the video now.
The Venn diagram of "shoots at drones" and "concerned with other people's safety" is two separate circles.
But anyway if you aren't rich enough to laugh off half a decade of court costs then you probably shouldn't shoot at them at all.