From what I've seen people like facing the door...

I remember I once got the choice window desk in a large office (very large - was actually a trading floor of sorts).

Whenever I came in on weekends I'd sit with my back to a massive, empty open space. It didn't feel like an issue when there were people around during the week - but when it was just me it really creeped me out. Eventually I swapped with a location that didn't have it's back to the open space.