Even if you could cure cancer or HIV with a vaccine it would have a relatively negligible impact compared to AGI.

There are far more signals that AGI is going to be achieved by OpenAI, Anthropic, DeepMind or X.ai within the next 5-10 years than there were of any other hyped breakthrough in the past 100 years that ultimately never came to fruition. Doesn't mean it's guaranteed to happen, but to ignore the multitude of trends which show no signs of stopping, it seems naive in Anno Domani 2025 to discount it as a likely possibility.