How could you not? At whatever point a crew member become disillusioned, it'll likely be too late to turnaround. There'll be a high incidences of interplanetary depression/psychosis as people struggle to deal with leaving the Blue Dot behind, esp. when they see footage from the earth, rainforests, etc. But, nothing counselling won't be able to take care of.
Right now, state propaganda is powerful enough to make young people line up to kill and be killed. So, a little interplanetary panic can be taken care of. In extreme cases, you can have protocols for any crew members who attempts to munity to euthanatized to guarantee the success of the mission.
My .02.