Admittedly they're getting fewer and fewer, but they exist.
The same is also true in GCP, so as much as I prefer GCP from a technical standpoint: the truth is, if you can't see it, it doesn't mean it goes away.
(There may still be some core IAM dependencies in USE1, but I haven’t heard of any.)
We'll know when (if) some honest RCAs come out that pinpoint the issue.
the Billing part of the console in eu-west-2 was down though, presumably because that uses us-east-1 dynamodb, but route53 doesn't.
R53 seems to use Dynamo to keep track of the syncing of the DNS across the name servers, because while the record was there and resolving, the change set was stuck in PENDING.
After DynamoDB came back up, R53's API started working.