We eat some thistles, which have basically the same issue - see artichokes. Gotta boil them to deactivate the needles, though I have no idea how the thistle and nettle needles compare biologically. Anyways, I guess my point is that it shouldn't be too hard to get Americans to eat these.

Every time I go out for hotpot, I get as many greens as possible; I love boiling them down in a tasty broth and chowing down on an entire football field of vegetables, sometimes wrapped around a piece of meat. I could see adding them in here easily.

There are also a lot of dishes you can add a big handful of chopped, frozen spinach to for some additional nutrition. These would be another incredible option in scenarios like that.

Blending it down to add a more herby flavor to a puree, or to bulk up a pesto, or something along those lines could work well.