For cars I found it interesting that my water pump on my Dodge Ram is stamped with Made in Italy. Yet the part is fairly small that even if Italy continues to make it, they can ship 50k water pumps in one shipping container to Detroit, and the truck can still be assembled here. That's not an issue. The issue is when the truck is made in Mexico entirely (which I think they still are). I know that's not "the entire supply chain" but it certainly becomes a center of gravity.
Last year many people were talking about dev shops changing their "center of gravity" from the US to other places like Poland. In other words, CEO here, EVERYTHING else is in Poland. Wherever that center of gravity is, that's the country that will benefit the most. They may even hire a remote worker in the US that is up all night - but it will be the exception, not the rule to hire US people.