1. Your frameworks are out of sync with the the rest of the system, could cause problems updating.
2. You're now running super-buggy development WebKit. The code you're using was written a few hours ago, remember that.
3. The old WebKit inspector doesn't have retina support. If you've got a rMBP and care about how it looks, don't do this.
4. The article gives no information on how to go "back" after you've done it.