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It has spent the entire 2020s trying to push through a global treaty allowing them to declare situations independently of national governments. The backlash has been huge, especially since this can have consequences going beyond healthcare.
WHO is, like every scientific or humanitarian endeavor, imperfect. But the list of goods they've done in the world dwarves the list of failures.
UNESCO, well, I'm looking at its website and Wikipedia article now, and I don't understand what it does. (Or maybe it would be easier to list what it doesn't do, since even its list of sponsored institutions is mind-numbingly long.)
The WHO has been trying to push through an international treaty since 2020 which would allow them to override national governments on health matters.
Any example of a diktat from on high which you think was highly negative? Afaik, these bodies typically just promote whatever is scientifically / economically / etc. the prevailing worldview