A simple regex filter will get rid of that. Now, if you use your own domain and have it configured as a catch-all, then you could do github@domain.tld.
Also, spammers generally don't seem to be going to the effort to apply regex filters to the data they've scraped...
But the email I used to interact with the Linux kernel mailing list I had to null route after a while, it got so much spam. I used a throwaway for just that purpose of course, so no big deal.
By far the worst one is always going to be something generic like contact@, but my email provider is very good at filtering out those appropriately. :)