I use uv here and there but have a bunch of projects using regular pip with pip-tools to do a requirements.in -> requirements.txt as a lockfile workflow that I've never seen enough value in converting over. uv is clearly much faster but that's a pretty minor consideration unless I were for some reason changing project dependencies all day long.

Perhaps it never grabbed me as much because I've been running basically everything in Docker for years now, which takes care of Python versioning issues and caches the dependency install steps, so they only take a long time if they've changed. I also like containers for all of the other project setup and environment scaffolding stuff they roll up, e.g. having a consistently working GDAL environment available instantly for a project I haven't worked on in a long time.