As someone who has also spent two decades wrangling C/C++ codebases, I wholeheartedly agree with every statement here.

I have an even stronger sentiment regarding cross compilation though - In any build system, I think the distinction between “cross” and “non-cross” compilation is an anti-pattern.

Always design build systems assuming cross compilation. It hurts nothing if it just so happens that your host and target platform/architecture end up being the same, and saves you everything down the line if you need to also build binaries for something else.