All I know is I used to have full on colds during winter in my 20s to early 30s, like every winter I would get two weeks of runny nose till the skin became red and irritated, sore and painful throat, coughing, etc. Since I take 25000 IU (D-Cure in Belgium) like 2-3 times a month during winter for the past 15+ years my cold last 2-3 days and symptoms are much more mild. For me the data is there.