When I was working on my thesis, I had an appendix of annotated source code that was generated by a series of Julia macros that effectively turned my code inside out to make a LaTeX document. The custom macro-comments became the bulk of the LaTeX source, the code got wrapped in some environment that presented it with syntax highlighting and all that.

I was halfway through implmenting the syntax highlighting Vim plugin for the resulting Julia-LaTeX hybrid format when I realized that I had an actual deadline coming up, and just accepted solid-color LaTeX source.