I've used models and tried to find exploitable edge from historical price data as in intention to do some automated trading. Edges that survives end-to-end fees are not that common and even if you find one, it might not beat holding Bitcoin for example. I could still find some opportunities but those were rare occasions, like 3-5 trades per year. I doubt that models could do better without guidance, not that I have that much expertise in these areas.

I did not dig that deep into prediction markets or sports betting, perhaps those would have more exploitable statistical angles.

I'm now building research archive from stock equities. I collected all publicly traded companies and what they have published, like: annual financials, interim financials, guidance information, corporate actions, prices. I have that data indexed in a database and I can do deep research on that easily. I asked a couple of models to find companies with best risk-reward for the end of the next quarter. The test has just started so can't say for sure how far just basic fundamental analysis gets me.

I could not find an easy way to make a profit so I'm doubtful that model on its own could very easily do it. Perhaps there are some ways though, like Silk Road was all online, so perhpas, theoretically, with abliterated model and little engouragement, it could rent VPS and hide that behind VPN port redirection and serve onion service for drug market. I don't think it's likely to happen but maybe not entirely impossible.