1) The chips don't reach 220C. The 220C is the temperature at the hot end of the heat pump. The chips are on the cold end of the heat pump.

2) The International Space Station has used a dual-loop ammonia/water-based heat pump to cool the station temperatures. It's been in place for several decades. Heat pumps are a proven technology.

Other satellites have also used heat pumps, such as SES-17 in geostationary orbit https://www.esa.int/Applications/Connectivity_and_Secure_Com...