Here's the official story from AWS:
https://aws.amazon.com/message/101925/
This, too, was contained to us-east-1:
"While the event started at 11:48 PM PDT on October 19 and ended at 2:20 PM PDT on October 20, there were three distinct periods of impact to customer applications. First, between 11:48 PM on October 19 and 2:40 AM on October 20, Amazon DynamoDB experienced increased API error rates in the N. Virginia (us-east-1) Region. Second, between 5:30 AM and 2:09 PM on October 20, Network Load Balancer (NLB) experienced increased connection errors for some load balancers in the N. Virginia (us-east-1) Region. This was caused by health check failures in the NLB fleet, which resulted in increased connection errors on some NLBs. Third, between 2:25 AM and 10:36 AM on October 20, new EC2 instance launches failed and, while instance launches began to succeed from 10:37 AM, some newly launched instances experienced connectivity issues which were resolved by 1:50 PM."