Agent A has internet access and the dangerous message, but no access to the secret company data, so nothing can get exfiltrated.
Agent B gets a tainted message from Agent A. Agent B can process the message using the secret company data. Agent B has no internet access and can only receive/send messages.
You can imagine an agent C that moves the work along or replies to an external user with the outcome.
Any workflow that has both an input and an output will complete the Lethal Trifecta as a whole, but no single agent does by itself. It raises the bar quite a lot, you need to confuse multiple agents in the loop to exfiltrate data.
Fun research, but it's a bit hard to see all my coworkers right now installing Claude desktop and moving on with no afterthought whatsoever...
Regarding infrastructure: my toy sandbox is just a docker-compose inspired YAML project file. So it's only containers. See my profile. The principle can be implemented anywhere you can run agents and cut network/data access though.