Regardless of whether you should depend on them, many many people do. Heck, many people don't even understand that there's a choice to be made: after all, everyone knows that Oracle is ACID compliant, right?
Yes, many don't support SERIALIZABLE. Didn't contradict that either.
Sorry, I was confused by the bit about "If your workload needs serializability, set it" since that's physically impossible on Oracle 11g.
Just because a DB has a replication package available (like MySQL) does not mean that it is a distributed system. And the file backed DBs (like Berkeley) are definitely not distributed. Sure, there are some extremely expensive massively parallel DBs in use (like Volt), but the number of deployments for those systems is a drop in the bucket compared with single-node MySQL/Postgres/Oracle/SQLServer/DB2 instances.