The one key element of a Skype Killer, which isn't present in WebRTC, is a prescribed infrastructure to support these communications. Skype is made up of users who actually are, usually, unaware that they are also routing calls for other users. Even more precarious (and absent from WebRTC) are the skype SuperNodes, which no one is going to redo for WebRTC.
The things which we love about skype, most notably the directory and ease of routing, are currently missing from WebRTC. Someone might come along and make them, but WebRTC is not inherently different from Skype's infrastructure, it's just new. Someone still has to build the supporting services to turn this into a Skype Killer.