Not really, read-line is more or less equivalent to python's input method. It reads raw input and tries to evaluate it. Passing false makes it safer for reading data structures, but it will still try to execute Java constructors so that your data is correctly initialized. To be safe you need to use other methods i.e. edn(extensible data notation).

edn limits what is allowed to a safe subset of what read-line will allow, all of the base clojure types and collection types (maps, lists, sets, vectors) are allowed, Java isn't.