House construction is insane, anyway -- they're full of random stuff, and there are plenty of non-accessible void spaces. Datacenters are at least generally nice and open, so finding a weird residential hidden fire
should be a lot easier. (which is why datacenters get permission to run their wiring the way they do, etc., because they have so much other safety)
The right thing to do in a real datacenter it to check which of your ~hundreds of laser VESDA sensors first tripped, and investigate in that area :) Presumably you have floor air supply, ceiling air return, so the first thing to trip should be a ceiling sensor near your fire. If no floor sensors trip, I wouldn't be super afraid to go in there, and if it's only a small number of them it's not a big fire.
You don't want the dry pipe to go off for sure, and you don't want the FM-200 either, but the consoles should be reporting the smoke alarm to you way before a human would smell it "filling the whole room", and they don't generally discharge either for very small events (at least everywhere I've seen).
In an office (some open plan, some cubicles, some conference rooms and offices, etc.), with a few racks of equipment, and maybe some lab space, it's a lot more similar to the scary hidden residential fire problem. :( Your risks in trying to uncover the problem are actually higher than in the datacenter because then you don't have the amazing gas system and a dry pipe backup to save you if it turns into a big fire while you're there, and it's not as designed for easy egress, and probably doesn't even have real EPO. I wonder if there's a firefighter on HN who would know the real answer to this case.