I don't really care about Gmail 'features' that I will be missing out on, spam detection is probably the thing I'll miss the most, but that's a tradeoff I can live with.

Other than that, there's the thing that I need to trust my VM provider, but that much easier than trusting a data mining conglomerate with your private conversations.

In the end, self hosting an email server isn't that big of a deal to set up and maintain.