I feel like, while using classical inheritance in JS is fine, it's an unfair simplification to say that creating classes in vanilla JS is painful. Prototypal inheritance is more powerful than classical inheritance, and the reason it takes a bunch of boilerplate to implement classes in JS is that you're basically narrowing down to a less powerful model.

The trouble is that a lot less energy has gone into designing for non-classical prototypal inheritance, and what techniques exist are unknown to most programmers.