http://en.wikipedia.org/wiki/Armstrong_Limit
http://en.wikipedia.org/wiki/Time_of_useful_consciousness
Also look at the TUC (time of useful consciousness) that it´s below 5 secs when flying that high. That means that you have less than 5 secs to put your oxigen mask on before you lose conciousness, or behave with out knowing what is happening. Also due to the extreme low pressure, you´ll have a horrible a horrible stomach ache due to the expansion of the gases inside you. Your blood (or at least the corporal fluids exposed directly to the low pressure) will start boiling.
Not funny. Maybe one solution could be wearing some kind of pressure suit for this trips. But that is not going to be very convinient..