not sure what you mean exactly, but one thing that has caused tons of trouble here, with sometimes the sole solution being a restart (ok our IT maintainer might be doing something worng, yet..) is the opposite: take a bunch of workstations and a bunch of servers, put home directories and data on servers then put everything together using NFS shares. Run analysis and whatnot on the data. Then make the server go down somehow and watch all workstation getting completely locked up without seemingly ever generating some kind of timeout error instead waiting endlessly on a dead connection.